WORK IN PROGRESS How likely are you to develop type 2 diabetes

Important: Make sure to have your genotyped genome saved in a folder onto your computer.

What is type 2 diabetes?

Overview

Type 2 diabetes is a chronic condition that affects the way your body metabolizes sugar (glucose) — an important source of fuel for your body.

With type 2 diabetes, your body either resists the effects of insulin — a hormone that regulates the movement of sugar into your cells — or doesn’t produce enough insulin to maintain normal glucose levels.

Type 2 diabetes used to be known as adult-onset diabetes, but today more children are being diagnosed with the disorder, probably due to the rise in childhood obesity. There’s no cure for type 2 diabetes, but losing weight, eating well and exercising can help manage the disease. If diet and exercise aren’t enough to manage your blood sugar well, you may also need diabetes medications or insulin therapy.

Symptoms

Signs and symptoms of type 2 diabetes often develop slowly. In fact, you can have type 2 diabetes for years and not know it. Look for:

  • Increased thirst
  • Frequent urination
  • Increased hunger
  • Unintended weight loss
  • Fatigue
  • Blurred vision
  • Slow-healing sores
  • Frequent infections
  • Areas of darkened skin, usually in the armpits and neck

Genome-wide association study(GWAS) is an observational study of a genome-wide set of genetic variants in different individuals to see if any variant is associated with a trait. GWASs typically focus on associations between single-nucleotide polymorphisms (SNPs) and traits like major human diseases, but can equally be applied to any other genetic variants and any other organisms. The SNPs in GWAS associated with type 2 diabetes

Step by step guide

Step 1: Download R and RStudio.

R: https://cloud.r-project.org

Rstudio: https://www.rstudio.com/products/rstudio/download/

Step 2:

sources: https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/symptoms-causes/syc-20351193

https://www.ebi.ac.uk/gwas/

AUTHOR: Balint